Does This Anti-Viral Herb Hold
The Key To Treating The Worlds Deadliest Viruses...
Avian Flu, Ebola and HIV?
Well before the Avian flu became
headline news, medical researchers have been researching compounds
in medicinal plants that already have shown clinical results
treating viral infections. By isolating the natural compound(s) that
demonstrate the strongest effect against a specific virus such as
the H5N1 virus the can then synthesis the molecule and develop a new
drug. Twenty Centuries of
Effective Anti-Viral Use
Canadian researchers(1) have been
investigating a number of the compounds from the anti-viral plant
Andrographis Paniculata.
With over 20 centuries of use in Chinese Medicine treating colds,
flu and respiratory infections Andrographis Paniculata
Extract has in modern times become a main treatment by doctors in
Scandinavia for flu, colds and sinusitis.
Slowing Deadly Virus Replication
Previous research(2)
demonstrated that Andrographolides (the standardized
compounds in Andrographis Paniculata Extract) reduce a
viruses ability to replicate by inhibiting the production of
glycoprotein in the virus.
Building on this knowledge they
isolated several of the individual Andrographolide compounds and
performed further testing. Many of the compounds proved helpful but
one, 14-dehydoandrographolide, showed the greatest effect of against
H5N1 Avian flu virus, Ebola Virus, and RSV(3).
Other Plants Have Similar Anti-Viral
Effect
Andrographis Paniculata is not
the only plant in which scientist have discovered the ability to
inhibit viral glycoprotein slowing its replication. Another plant is
Schizandra Chinesis has a Dibenzocyclooctadiene lingnans
in it's extract which also inhibits viral glycoprotein(4).
Of course there are other plants which
have demonstrated anti-viral activity through different mechanisms
and against other viruses. For example the compounds Oleuropein &
Lucidumoside in Lingustum Lucidum have an anti-viral
activity against parainfluenza, Respiratory Syncytial Virus (RSV),
herpes mononucleosis, hepatitis virus, rotovirus, bovine rhinovirus,
canine parvovirus and feline leukaemia virus in human.
The Good News and Bad News
First the bad news. In spite of all the
activity around avian flu most likely it will be years before a
pharmaceutical company delivers such a drug to market. Which will
only occur when they can produce a unique drug over which they have
sole patent rights. The good
news is that a lot of research is happening through out the world to
find and develop vaccines, drugs and medicinal plants that may hold
the key to fighting many deadly viruses.
You Can Fight Common Cold & Flu Viruses
With Anti-Viral Plants
While Avian Flu may be getting the headlines, everyday flu and
common colds affect millions during flu season. Fortunately the full
spectrum plant extracts mentioned above are available as over the
counter dietary supplements.
All have a long history of safe with remarkable studies revealing
results such as; reducing the risk of colds by 2.1X, shortening the
duration of flu by 87% over the amatadine control group and
improving cold symptoms by 535%.
Click to Learn More.
Research References
1. Ajoy BASAK, Mei ZHONG, Jon
S. MUNZER, Michel CHRETIEN and Nabil G. SEIDAH, Implication of the
proprotein convertases furin, PC5 and PC7 in the cleavage of surface
glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses:
a comparative analysis with fluorogenic peptides. Laboratory
of Molecular Medicine and Disease of Ageing Centre, Loeb Health
Research Institute, Ottawa Civic Hospital, and Laboratory of
Biochemical Neuroendocrinology, and the Protein Engineering Network
of Centres of Excellence, Clinical Research Institute of Montreal.
2. Yao, X. J., Wainberg, M. A. and Parniak, M. A. (1992) Virology
187, 56±62
3. Basak A, Cooper S, Roberge AG, et al.
Inhibition of proprotein convertases-1, -7 and furin by diterpines
of Andrographis paniculata and their succinoyl esters. Biochem J
1999;338 ( Pt 1):107-113.
4. Pan Q, Lu Q, Zhang K, Hu X.
Dibenzocyclooctadiene lingnans: a class of novel inhibitors of
P-glycoprotein. Cancer Chemother Pharmacol. 2005 Oct 18;:1-8
5. Fredrickson W. R., U.S.
Patent 6117844; Appl. No. 668324; September
12, 2000. 6. Shuang-Cheng MA,
Zhen-Dan HE, Xue-Long DENG, Paul Pui-Hay BUT, Vincent Eng-Choon OOI, Hong-Xi
XU, Spencer Hon-Sun LEE and Song-Fong LEE In Vitro Evaluation of Secoiridoid
Glucosides from the Fruits of Ligustrum lucidum as Antiviral Agents.
Chem Pharm Bull (Tokyo). 2001 Nov;49(11):1471-3. |
