500 to 1000 milligrams of root capsules taken 3 times daily or
250 to 500 milligrams of extract taken 4 times daily
Pediatric: Astragalus may be used in children to support the
immune system. The
dose should be determined by adjusting the recommended adult dose to
account for the child's weight. Most herbal dosages for adults are
calculated on the basis of a 150 lb (70 kg) adult. Therefore, if the
child weighs 50 lb (20 to 25 kg), the appropriate dose of astragalus
for this child would be 1/3 of the adult dosage. This dose should be
taken once daily for up to one month.
Product With
Astragalus
AvaFlu Advanced Formula Cold, Flu, Sinusitis,
Immune
Booster
Astragalus Membranaceus
Research
1) Khoo KS, Ang PT. Extract of astragalus membranaceus and
ligustrum lucidum does not prevent cyclophosphamide-induced
myelosuppression. Singapore Med J. 1995 Aug;36(4):387-90.
2) Sun Y, Hersh EM, Lee SL, McLaughlin M, Loo TL, Mavligit GM.
Preliminary observations on the effects of the Chinese medicinal
herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte
blastogenic responses. J Biol Response Mod. 1983;2(3):227-37.
3) Kitagawa I, Wang H, Takagi A, et al. Chemical constituents of
Astragali radix, the root of Astragalus membranaceus bunge.(1).
Cycloastragenol, the 9,19-cyclolanostane-type aglycone
astragalosides, and the artifact aglycone astrgenol. Chem Pharm Bull
1983;31:689.
4) Kitagawa I, Wang H, Saito M, et al. Chemical constituents of
Astragali radix, the root of Astragalus membranaceus bunge. (2).
Astragalosides, I, II, IV, acetylastragaloside I and
isoastragalosides I and II. Chem Pharm Bull 1983;31:698.
5) Kitagawa I, Wang H, Saito M, Yoshikawa M. Chemical
constituents of Astragali radix, the root of Astragalus membranaceus
bunge. (3). Astragalosides III, V, and VI. Chem Pharm Bull
1983;31:709.
6) He Z, Findlay J. Constituents of Astragalus membranaceus. J
Nat Prod 1991;54:810.
7) Kitagawa I, Wang H, Yoshikawa M. Chemical constituents of
Astragali radix, the root of Astragalus membranaceus bunge. (4).
Astragalosides VII and VIII. Chem Pharm Bull 1983;31:716.
8) Lin LZ, He XG, Lindenmaier M, et al. Liquid chromatography-electrospray
ionization mass
spectrometry study of the flavonoids of the roots of Astragalus
mongholicus and A. membranaceus. J Chromatogr A 2000;876:87-95.
9) Mills S, Bone K. Principles and Practice of Phytotherapy.
Edinburgh, Scotland: Churchill
Livingstone; 2000:273-279.
10) Jiao Y, Wen J, Yu X. Influence of flavonoid of Astragalus
membranaceus’s stem and leaves on the function of cell mediated
immunity in mice. Zhongguo Zhong Xi Yi Jie He Za Zhi
1999;19:356-358.
11) Toda S, Shirataki Y. Inhibitory effects of Astragali radix, a
crude drug in Oriental medicines, on lipid peroxidation and protein
oxidative modification by copper. J Ethnopharmacol 1999;68:331-333.
12) Wang D, Shen W, Tian Y, et al. Protective effect of active
components extracted from Radix astragali on human erythrocyte
membrane damages caused by reactive oxygen species. Zhongguo Zhong
Yao Za Zhi 1996;21:746-748, 763.
13) Chen LX, Liao JZ, Guo WQ. Effects of Astragalus membranaceus
on left ventricular function and oxygen free radical in acute
myocardial infarction patients and mechanism of its cardiotonic
action. Zhongguo Zhong Xi Yi Jie He Za Zhi 1995;15:141-143.
14) Wang DC. Influence of Astragalus membranaceus (AM)
polysaccharide FB on immunologic function of human periphery blood
lymphocyte. Zhonghua Zhong Liu Za Zhi 1989;11:180-183.
15) Zhao XZ. Effects of Astragalus membranaceus and Tripterygium
hypoglancum on natural killer cell activity of peripheral blood
mono-nuclear in systemic lupus erythematosus. Zhongguo Zhong Xi Yi
Jie He Za Zhi 1992;12:679-671,645.
16) Chu DT, Lin JR, Wong W. The in vitro potentiation of LAK cell
cytotoxicity in cancer and AIDS patients induced by F3 - a
fractionated extract of Astragalus membranaceus. Zhonghua Zhong Liu
Za Zhi 1994;16:167-171.
17) Weng XS. Treatment of leucopenia with pure Astragalus
preparation - an analysis of 115
leucopenic cases. Zhongguo Zhong Xi Yi Jie He Za Zhi
1995;15:462-464.
18) Huang ZQ, Qin NP, Ye W. Effect of Astragalus membranaceus on
T-lymphocyte subsets in patients with viral myocarditis. Zhongguo
Zhong Xi Yi Jie He Za Zhi 1995;15:328-330.
19) Yuan WL, Chen HZ, Yang YZ, et al. Effect of Astragalus
membranaceus on electric activities of cultured rat beating heart
cells infected with Coxsackie B-2 virus. Chin Med J
1990;103:177-182.
20) Yang YZ, Jin PY, Guo Q, et al. Effect of Astragalus
membranaceus on natural killer cell activity and induction of alpha-
and gamma-interferon in patients with Coxsackie B viral myocarditis.
Chin Med J 1990;103:304-307.
21) Qian ZW, Mao SJ, Cai XC, et al. Viral etiology of chronic
cervicitis and its therapeutic response to a recombinant interferon.
Chin Med J 1990;103:647-651.
22) Yoshida Y, Wang MQ, Liu JN, et al. Immunomodulating activity
of Chinese medicinal herbs and Oldenlandia diffusa in particular.
Int J Immunopharmacol 1997;19:359-370.
23) Wang Y, Qian XJ, Hadley HR, Lau BH. Phytochemicals potentiate
interleukin-2 generated lymphokine-activated killer cell
cytotoxicity against murine renal cell carci-noma. Mol Biother
1992;4:143-146.
24) Zee-Cheng RK. Shi-quan-da-bu-tang (ten significant tonic
decoction), SQT. A potent Chinese biological response modifier in
cancer immunotherapy, potentiation and detoxification of anticancer
drugs. Methods Find Exp Clin Pharmacol 1992;14:725-736.
25) Lau BH, Ruckle HC, Botolazzo T, Lui PD. Chinese medicinal
herbs inhibit growth of murine renal cell carcinoma. Cancer Biother
1994;9:153-161.
26) Purmova J, Opletal L. Phytotherapeutic aspects of diseases of
the cardiovascular system. 5. Saponins and possibilities of their
use in prevention and therapy. Ceska Slov Farm 1995;44:246-251.
27) Luo HM, Dai RH, Li Y. Nuclear cardiology study on effective
ingredients of Astragalus membranaceus in treating heart failure.
Zhongguo Zhong Xi Yi Jie He Za Zhi 1995;15:707-709.
28) Li SQ, Yuan RX, Gao H. Clinical observation on the treatment
of ischemic heart disease with Astragalus membranaceus. Zhongguo
Zhong Xi Yi Jie He Za Zhi 1995;15:77-80.
29) Lei ZY, Qin H, Liao JZ. Action of Astragalus membranaceus on
left ventricular function of angina pectoris. Zhongguo Zhong Xi Yi
Jie He Za Zhi 1994;14:199-202,195.
30) Hong CY, Ku J, Wu P. Astragalus membranaceus stimulates human
sperm motility in vitro. Am J Chin Med 1992;20:289-294.
31) Miller LG. Herbal medicinals: selected clinical
considerations focusing on known or potential drug-herb
interactions. Arch Intern Med 1998;158:2200-2211.
32) Chang H, But P. Pharmacology and Applications of Chinese
Materia Medica, Vol 2. Singapore: World Scientific; 1987:1041-1046.
33) Peng T, Riesemann H, Kandolf R. The inhibitory effect of
Astragalus membranaceus on coxsackie B3
virus RNA replication. Chin Med Sci J 1995;10:146-150.
34) Guo Q, Peng TQ, Yang YZ. Effect of Astragalus membranaceus on
Ca 2 + influx and coxsackie virus
B3 replication in cultured neonatal rat heart cells. Chung Kuo Chung
Hsi I Chieh Ho Tsa Chih
1995;15:483-485.
35) He J, Li Y, Wei S, et al. Effect of mixture of Astragalus
membranaceus, Fructus Ligusti lucidum and Eclipta prostrata on
immune function in mice. Hua Hsa I Ko Ta Hseuh Hseuh Pao
1992;23:408-411.
36) Upton R, ed. Astragalus Root: Analytical, quality control,
and therapeutic monograph. Santa Cruz, CA: American Herbal
Pharmacopoeia. 1999:1-25.
37) Zhao KS, Mancini C., Doria G. Enhancement of immune response
in mice by Astragalus membranaceus extracts. Immunopharmacology
Nov-Dec;20(3):225-33. 1990
38) Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on
the effects of the Chinese medicinal herbs Astragalus membranaceus
and Ligustrum lucidum on lymphocyte blastogenic responses.
39) Shao CR, Chen FM Tang YX. Clinical and experimental study on
Ligusticum wallichi mixture in preventing and treating bronchial
asthma. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1994;14:465-468.
40) Chen KJ, Chen K. Ischemic stroke treated with Ligusticum
chuanxiong. Chin Med J 1992;105: 870-873.
41) Shao CR, Chen FM Tang YX. Clinical and experimental study on
Ligusticum wallichi mixture in preventing and treating bronchial
asthma. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1994;14:465-468.
42) Purmova J, Opletal L. Phytotherapeutic aspects of diseases of
the cardiovascular system. 5. Saponins
and possibilties of their use in prevention and therapy. Ceska Slov
Farm 1995;44:246-251.
43) Luo HM, Dai RH, Li Y. Nuclear cardiology study on effective
ingredients of Astragalus membranaceus in treating heart failure.
Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1995;15:707-709.
44) Zhao KW, Kong HY. Effect of Astragalan on secretion of tumor
necrosis factor in human peripheral mononuclear cells. Chung Kuo Hsi
I Chieh Ho Tsa Chih 1993;13:263-265.
