The Healing Power
The Benefits of Bromelain
The next time you are in a
topical location and you have one of the following;
sprains, strains, cuts, bruises, insect bits,
joint pain, muscle pain, sinusitis, or arthritis, you may
want enjoy a fresh pineapple.
Besides being a healthful fruit,
pineapple contains an enzyme called Bromelain that has some
Inflammation, Swelling and Healing
most significant property of Bromelain is it's ability to
reduce inflammation, pain, swelling and speed healing from
injuries, trauma and surgery(2,3,7,8,9,11,13,14,15,16,19,22,24,25,26,28,34,36).
examples of it's effectiveness include the following.
- In studies of Bromelain's
anti-inflammatory power it has been found as or more
effective and much better tolerated by patients than the
following drugs; Naproxen (Aleve),
Piroxicam (Feldene), Ketoprofen
Etodolac (Lodine), Diclofenac
- In a
1995 German study(14) of people with strains and torn
found that bromelain caused a significant reduction in swelling,
tenderness, and pain, both at rest and during movement.
- Supplementation of
bromelain reduced the average number of days after surgery
for complete disappearance of pain from 3.5 to 1.5, and
disappearance of inflammation from 6.9 to 2.0 days, as
compared with controls receiving no bromelain(24).
A clinical study of boxers with
bruises on the face and hematomas of
the orbits, lips, ears, chest and arms reported complete disappearance for 80.6% of those taking Bromelain
in 4 days vs. only 13.8% of those in the placebo group(20).
These properties make
Bromelain helpful for typical injuries that occur during summer
sports activities or home improvement projects. Especially when
combined with a herbal pain
reliever such as Devils Claw Extract and Glucosamine which aids both in
healing tissue as well as joint repair.
How to Eliminate
Joint, Muscle and Back Pain Even When Other Treatments Fail
Click to Read More
For those who
suffer from osteoarthritis or rheumatoid arthritis bromelain can be
helpful improving pain, inflammation and mediating the autoimmune
response(3, 31, 32, 33, 34, 35).
Here are some
findings from relevant studies.
improvement in patients with knee osteoarthritis was
demonstrated by using bromelain in both the primary
outcome (symptoms assessed by the Western Ontario McMaster
University Arthritis Index, WOMAC) and in the secondary
outcomes (overall psychological wellbeing)(35).
29 subjects whom
suffered from arthritis (25 subjects had rheumatoid arthritis,
2 had osteoarthritis, 1 had both and the last had gout) and had
residual swelling in a joint after long-term steroid therapy. After
starting the bromelain therapy soft tissue swelling subsided
mostly, or completely, in 72.4 % of the subjects.(3)
If you take
glucosamine for your arthritis bromelain can enhance the
by up to 90%(30). It also increases the absorption of
sulfur (important for joint health) by up to 50%(30).
Bromelain can prevent
or minimize the severity of angina pectoris and transcient ischemic
attacks and is useful in the prevention and treatment of thrombosis
and thrombophlebitis. It appears that this is the results of it's
ability to break down
cholesterol plaques, exert a potent fibrinolytic activity and it's
Below are the results
of some cardiovascular studies on bromelains' effect.
- Administration of bromelain to patients
with angina pectoris resulted in the disappearance of symptoms in all patients
within 4 to 90 days.(38) Similar results have
been observed in patients taking bromelain. After
discontinuing bromelain, angina attacks reappear after a variable period of
time, often triggered by stressful experiences.(37)
- A drastic reduction in the incidence of coronary infarct
after administration of potassium and magnesium orotate along with 120-400 mg of
bromelain per day has also been reported.(39)
- In a study involving 73 patients with acute thrombophlebitis,
bromelain, in addition to analgesics, was shown to decrease all symptoms of
inflammation; including, pain, edema, tenderness, skin temperature, and
Sinusitis and Bronchitis
Bromelain has been
shown helpful for upper respiratory tract infections such as
Sinusitis and Bronchitis.
Bromelain helps to reducing nasal inflammation and break up the
mucus in the nasal, sinus and respiratory areas.(18,
21, 26, 27, 30)
In the patients not
receiving antibiotic treatment, 85% of patients receiving
bromelain had complete resolution of inflammation of the nasal
mucosa and complete resolution of breathing difficulties. Only
40% of the placebo group had a similar outcome with respect to
inflammation, while 53% reported resolution of breathing difficulty.(18)
Other Benefits of
properties of Bromelain include its use as a digestive aid and
indications that it may be helpful healing ulcers(1,
OK... So How Many
Pineapples Do I Need to Eat?
The typical dose
recommended for Bromelain by the German Commission E (The German
regulatory agency for herbal treatments) is 80mg - 320mg two to
three time a day.
This would translate
into about 1 to 8 raw pineapples per day. Bromelain is destroyed by
cooking heat so you must eat your pineapple uncooked.
Bromelains' effect is
dose dependent. For most of the above conditions above best
results tend to be with a dosage of 460mg to
1,000mg per day.
So maybe we should
say "a pineapple a day keeps the doctor away".
of the natural
anti-inflammatory and healing power of Bromelain plus it's ability
to enhance other natural ingredients such as Glucosamine and MSM it
is an essential ingredient in any natural anti-inflammatory pain
reliever. Especially those for which are intended to aid arthritis,
joint pain or pain caused by strains or trauma injuries.
Bromelain is just one
of the effective natural ingredients in our
and healing formula
Relevant Research and Studies
Blonstein JL. Control of
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Neubauer RA. A plant protease for potentiation of and
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Rovenska E, Svik K,
Stancikova M, Rovensky J. Inhibitory effect of enzyme therapy and
combination therapy with cyclosporin A on collagen-induced
arthritis. Research Institute of Rheumatic Diseases, Nabrezie I.
Krasku 4, 921 01 Piest'any, Slovak Republic.
Rheumatol. 2001 May-Jun;19(3):303-9.
Bazzichi L, Soletti
AL, Ciompi ML, Garzelli C. Activation of murine autoreactive b
cells by interleukin 1-like factors released from synovial
inflammatory cells of rheumatoid arthritis patients. Institute of
Medical Pathology, University of Pisa.
Ridderstad A, Lettesjo H, Strom H, Moller E. Protein-G binding
material from synovial fluid of rheumatoid arthritis patients
induces unorthodox autoantibodies (IgG1 rheumatoid factor) in NZB,
NZW and (NZB x NZW)F1 mice.
- Balakrishnan V, Hareendran A, Nair CS.
Double-blind cross-over trial of an enzyme preparation in
pancreatic steatorrhoea. J Assoc Phys India 1981; 29(3):207-209.
- Cirelli MG. Five years of clinical
experience with bromelains in therapy of edema and inflammation in
postoperative tissue reaction, skin infections and trauma. Clin
- Cohen A, Goldman J. Bromelains therapy
in rheumatoid arthritis. Penn Med J 1964;67:27-30.
- Cowie DH, Fairweather DV, Newell DJ. A
double-blind trial of bromelains as an adjunct to vaginal plastic
repair operations. J Obstet Gynaecol Br Commonw
- Gerard G. [Anticancer treatment and
bromelains]. Agressologie 1972;13(4):261-274.
- Glade MJ, Kendra D, Kaminski MV.
Improvement in protein utilization in nursing-home patients on
tube feeding supplemented with an enzyme product derived from
Aspergillus niger and Bromelain. Nutrition 2001;17(4):348-350.
- Gylling U, Rintala A, Taipale S, et al.
The effect of a proteolytic enzyme combinate (bromelain) on the
postoperative oedema by oral application. A clinical and
experimental study. Acta Chir Scand 1966;131(3):193-196.
- Hotz G, Frank T, Zoller J, et al. [Antiphlogistic
effect of bromelaine following third molar removal]. Dtsch
Zahnarztl Z 1989;44(11):830-832.
- Howat RC, Lewis GD. The effect of
bromelain therapy on episiotomy wounds--a double blind controlled
clinical trial. J Obstet Gynaecol Br Commonw 1972;79(10):951-953.
- Hunter RG, Henry GW, Civin WH. The
action of papain and bromelain on the uterus. Part III. The
physiologically incompetent internal cervical os. Am J Obst Gynec
- Korlof B, Ponten B, Ugland O.
Bromelain--a proteolytic enzyme. Scand J Plast Reconstr Surg
- Kugener H, Bergmann D, Beck K. [Efficacy
of bromelain in pancreatogenic digestive insufficiency].
Zeitschrift fur Gastroenterologie 1968;6:430-433.
- Mader H. [Comparative studies on the
effect of bromelin and oxyphenbutazone in episiotomy pains].
Schweiz Rundsch Med Prax 1973;62(35):1064-1068.
- Masson M. [Bromelain in blunt injuries
of the locomotor system. A study of observed applications in
general practice]. Fortschr Med 1995;113(19):303-306.
- Miller JM, Ginsberg M, McElfatrick GC,
et al. The administration of bromelain orally in the treatment of
inflammation and edema. Exper Med Surg 1964;22:293-299.
- Morrison AW, Morrison MC. Bromelain - a
clinical assessment in the post-operative treatment of
arthrotomies of the knee and facial injuries. Brit J Clin Pract
- Mudrak J, Bobak L, Sebova I. Adjuvant
therapy with hydrolytic enzymes in recurrent laryngeal
papillomatosis. Acta Otolaryngol Suppl 1997; 527:128-130.
- Ryan RE. A double-blind clinical
evaluation of bromelains in the treatment of acute sinusitis.
- Seligman B. Bromelain: an
anti-inflammatory agent. Angiology 1962;13:508-510.
- Seligman B. Oral bromelains as adjuncts
in the treatment of acute thrombophlebitis. Angiology
- Seltzer AP. Adjunctive use of bromelains
in sinusitis: a controlled study. Eye Ear Nose Throat Mon
1967;46(10):1281, 1284, 1286-1288.
- Spaeth GL. The effect of bromelains on
the inflammatory response caused by cataract extraction: a
double-blind study. Eye Ear Nose Throat Mon 1968;47(12):634-639.
- Stange R, Schneider R, Maurer R et al.
Proteolytic enzyme bromelaine enhances zytotoxicity in patients
with breast cancer [abstract]. Nat Scien Conf Compl Altern Integ
Med Res, Boston, MA, April 12-14, 2002.
- Tassman GC, Zafran JN, Zayon GM. A
double-blind crossover study of a plant proteolytic enzyme in oral
surgery. J Dent Med 1965;20(2):51-54.
- Tassman GC, Zafran JN, Zayon GM.
Evaluation of a plant proteolytic enzyme for the control of
inflammation and pain. J Dental Med 1964;19(2):73-77.
- Taub SJ. The use of bromelains in
sinusitis: a double-blind clinical evaluation. Eye Ear Nose Throat
- Weiss S, Scherrer M. [Crossed
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in chronic bronchitis]. Schweiz Rundsch Med Prax
- Zatuchni GI, Colombi DJ. Bromelains
therapy for the prevention of episiotomy pain. Obstet Gynecol
Department of Immunology, Arrhenius Laboratories for Natural
Sciences, Stockholm University, Sweden.
Eur J Immunol.
Klein G, Kullich W.
Reducing pain by oral enzyme therapy in rheumatic diseases.
Walker AF, Bundy R,
Hicks SM, Middleton RW. Bromelain reduces mild acute knee pain and improves well being
in a dose dependant fashion in an open study of otherwise healthy adults.
Inoue K, Motonaga A, Nishimura T,
Yokota M, Miki N, Fujisawa H, Ueda F, Shibata Y, Kimura K. Mechanism
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Arzneimittelforschung. 1991 Mar;41(3):235-9.
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Nieper HA. Effect of bromelain on coronary heart disease
and angina pectoris. Acta Med Empirica 1978;5:274-278.
Nieper HA. Decrease of the incidence of coronary heart
infarct by Mg- and K-orotate and bromelain. Acta Med Empirica 1977;12:614-618.
Seligman B. Bromelain-an anti-inflammatory agent thrombophlebitis. No toxicity. Angiology 1962;13:508-510.
Seligman B. Oral bromelains as adjuncts in the treatment
of acute thrombophlebitis. Angiology 1969;20:22-26.
Gutfreund A, Taussig S, Morris A. Effect of oral
bromelain on blood pressure and heart rate of hypertensive patients. Haw Med